N HeLa cells it was estimated that proteasomes are quite abundant constituting 0.6 of the cell bulk protein and have a half life of approximately 5 days [6]. Proteasomes in HeLa cells degrade defective ribosomal products (DriPs) at a rate of 1 ?106/min, and proteins that make it to the cellular pool at a slower rate, i.e. 6 ?105/min [3]. Similar numbers were obtained for L929 cells [7], but prot
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