Al and Cterminal domains, respectively, of eIF2a.Rothenburg et al. BMC Microbiology 2011, 11:56 http://www.biomedcentral.com/1471-2180/11/Page 4 ofYeast-based assays were previously employed to characterize PKR and its interaction with viral inhibitors [34,40,42,43]. To test whether vIF2a can inhibit PKRmediated toxicity in yeast, we transformed a control strain and a strain expressing human PKR u
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